Elevated plasma F2-isoprostane levels in schizophrenia
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چکیده
منابع مشابه
Key issues in F2-isoprostane analysis.
A large body of evidence indicates that measurement of F2-isoprostanes, specific prostaglandin F2-like compounds derived from the non-enzymatic peroxidation of arachidonic acid, is a reliable biomarker of oxidant stress in the human body. Since the discovery of F2-isoprostanes in the early 1990s, a variety of analytical approaches has been introduced for the quantification of these novel compou...
متن کاملBiological variation of plasma F2-isoprostane-III and arachidonic acid in healthy individuals.
bladder cancer risk. Cancer Res 1991;51:2762–7. 19. Lee DH, Yang SC, Hong SJ, Chung BH, Kim IY. Telomerase: a potential marker of bladder transitional cell carcinoma in bladder washes. Clin Cancer Res 1998;4:535–8. 20. Mostofi FK, Sobin LH, Torloni H. Histologic typing of urinary bladders. In: International histological classification of tumors. Geneva: World Health Organization, 1973:36. 21. S...
متن کاملClassifying oxidative stress by F2-Isoprostane levels in human disease: The re-imagining of a biomarker☆
Oxidative stress as classified by F2-Isoprostanes (F2-IsoPs) in Human Disease: Grab the Low-Hanging Fruit – The utility of F2-IsoPs as a biomarker of oxidative injury in human disease is complex. Careful consideration of the formation, metabolism, and measurement of this biomarker is imperative in the design of clinical trials. Conditions with significantly elevated levels of F2-IsoPs are ideal...
متن کاملLow-dose angiotensin II increases free isoprostane levels in plasma.
Chronic intravenous infusion of subpressor doses of angiotensin II causes blood pressure to increase progressively over the course of several days. The mechanisms underlying this response, however, are poorly understood. Because high-dose angiotensin II increases oxidative stress, and some compounds that result from the increased oxidative stress (eg, isoprostanes) produce vasoconstriction and ...
متن کاملRacial differences in urinary F2-isoprostane levels and the cross-sectional association with BMI
Levels of four urinary F(2)-isoprostanes (F(2)-IsoPs) were examined in a large sample of the Insulin Resistance Atherosclerosis Study (IRAS) multiethnic cohort: 237 African Americans (AAs), 342 non-Hispanic whites (NHWs), and 275 Hispanic whites (HWs). F(2)-IsoP isomers - iPF2a-III, 2,3-dinor-iPF2a-III, iPF2a-VI, and 8,12-iso-iPF2a-VI - were measured in 854 urine samples using liquid chromatogr...
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ژورنال
عنوان ژورنال: Schizophrenia Research
سال: 2016
ISSN: 0920-9964
DOI: 10.1016/j.schres.2016.06.011